A Sunshine State battle between No. 8 Florida (-7.5) and Miami (Fla). kicks off the 2019 college football schedule on Saturday, Aug. 24 at 7 p.m. ET. That's followed by Arizona at Hawaii on CBS Sports Network later that evening, a game in which the visiting Wildcats are 11-point favorites in the latest 2019 college football odds. That two-game appetizer sets up a full Week 1 college football schedule beginning on Thursday, Aug. 28. The latest Week 1 college football odds show No. 1 Clemson as a 35.5-point favorite against Georgia Tech, No. 2 Alabama at -34.5 against Duke and No. 3 Georgia going off at -20.5 against SEC East foe Vanderbilt in Nashville. Whether you're thinking about making college football predictions on one of those games or looking further down the board, a little unbiased advice can go a long way. Before you head to the window, see the Week 1 college football picks and predictions from the proven computer model at SportsLine.